SCHEMBL10019970

SCHEMBL10019970

CCOc1ccc2c(c1F)C(F)(F)C(F)(F)c1c-2ccc(I)c1F

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.32
FGFR2 P21802 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
PDK2 Q15119 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
KDM1A O60341 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019809 0.86 FGFR2 (0.36) FGFR1FGFR2L3MBTL1PDK2CYP1A2
SCHEMBL19621897 0.84 KDM4E (0.39) FGFR1FGFR2
SCHEMBL10020073 0.82 ALDH1A1 (0.36) FGFR1FGFR2PDK2PTGS1PTGS2
SCHEMBL10019969 0.82 L3MBTL1 (0.41) FGFR1FGFR2L3MBTL1PDK2CYP1A2
SCHEMBL10019908 0.82 L3MBTL1 (0.41) FGFR1FGFR2L3MBTL1PDK2CYP1A2
SCHEMBL10020112 0.81 CTSL (0.36) FGFR1FGFR2L3MBTL1PDK2
SCHEMBL10020119 0.81 PKM (0.34) FGFR1FGFR2L3MBTL1PDK2
SCHEMBL10019621 0.81 PKM (0.34) FGFR1FGFR2L3MBTL1PDK2
SCHEMBL29742117 0.80 L3MBTL1 (0.40) FGFR1FGFR2L3MBTL1CYP1A2CYP2D6
SCHEMBL2821417 0.80 L3MBTL1 (0.40) FGFR1FGFR2L3MBTL1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed