SCHEMBL10019982

SCHEMBL10019982

C=CCCc1ccc(-c2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.36
GABRA1 P14867 4/20 0.35
GABRB2 P47870 4/20 0.35
FGFR2 P21802 2/20 0.33
FGFR1 P11362 1/20 0.33
CNR2 P34972 2/20 0.32
PTPRC P08575 1/20 0.31
RET P07949 1/20 0.31
KDR P35968 1/20 0.31
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019984 0.88 NAAA (0.39) NAAAGABRA1GABRB2FGFR2FGFR1
SCHEMBL10019911 0.87 CTSL (0.32) GABRA1GABRB2
SCHEMBL10020161 0.87 RXRG (0.36) NAAAGABRA1GABRB2
SCHEMBL10019994 0.86 CTSS (0.37)
SCHEMBL10019663 0.86 FFAR1 (0.34) NAAA
SCHEMBL10019974 0.85 CTSL (0.30)
SCHEMBL10019966 0.85 FFAR4 (0.36) GABRA1GABRB2FGFR2FGFR1
SCHEMBL10020128 0.85 CTSL (0.33) GABRA1GABRB2
SCHEMBL10020178 0.84 HCRTR1 (0.30)
SCHEMBL10020191 0.83 PKM (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed