SCHEMBL10019984

SCHEMBL10019984

CCCc1ccc(-c2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)cc1F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
GABRA1 P14867 4/20 0.38
GABRB2 P47870 4/20 0.38
FGFR2 P21802 2/20 0.35
FGFR1 P11362 1/20 0.35
PTPRC P08575 1/20 0.34
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
RET P07949 5/20 0.33
KDR P35968 3/20 0.33
ALOX5 P09917 1/20 0.32
KDM1A O60341 2/20 0.32
ATM Q13315 1/20 0.31
FPR2 P25090 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019982 0.88 NAAA (0.36) NAAAGABRA1GABRB2FGFR2FGFR1
SCHEMBL22809285 0.88 GABRA1 (0.44) NAAAGABRA1GABRB2FGFR2FGFR1
SCHEMBL19621940 0.86 CTSL (0.32) CTSLCTSSCTSKALOX5
SCHEMBL10019995 0.86 L3MBTL1 (0.38) NAAAFGFR2FGFR1PTPRCKDM1A
SCHEMBL10019899 0.85 CTSL (0.40) NAAAGABRA1GABRB2CTSLCTSS
SCHEMBL10020139 0.85 RXRG (0.39) NAAAGABRA1GABRB2CTSLCTSS
SCHEMBL10019630 0.84 CACNA1C (0.36) NAAAGABRA1GABRB2CTSLCTSS
SCHEMBL10020037 0.84 GABRA1 (0.37) NAAAGABRA1GABRB2CTSLCTSS
SCHEMBL10019980 0.84 CTSS (0.46) NAAAGABRA1GABRB2CTSLCTSS
SCHEMBL10019989 0.83 FFAR4 (0.39) GABRA1GABRB2FGFR2FGFR1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed