SCHEMBL10020185

SCHEMBL10020185

CCOc1ccc(CCc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
KDM1A O60341 2/20 0.32
NAAA Q02083 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
CALM1 P0DP23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020114 0.96 CTSL (0.41) CTSLCTSSCTSKKDM1A
SCHEMBL10019899 0.93 CTSL (0.40) CTSLCTSSCTSKKDM1ANAAA
SCHEMBL10020128 0.90 CTSL (0.33) CTSLCTSSCTSK
SCHEMBL10019849 0.90 GABRA1 (0.36) CTSLCTSSCTSKCALM1
SCHEMBL10019631 0.90 CTSL (0.39) CTSLCTSSCTSK
SCHEMBL10019980 0.89 CTSS (0.46) CTSLCTSSCTSKNAAA
SCHEMBL10019836 0.88 CALM1 (0.36) L3MBTL1CALM1
SCHEMBL10020035 0.88 CACNA1C (0.34) KDM1ANAAA
SCHEMBL10019665 0.88 PKM (0.34) KDM1ANAAAL3MBTL1
SCHEMBL10020133 0.88 PKM (0.34) CTSLCTSSCTSKKDM1ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed