SCHEMBL1002059

SCHEMBL1002059

CCCCCC[SiH2]O[SiH2]O[SiH3]

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2761420 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL30183845 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL3652197 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL1332011 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL1330675 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL1000117 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL11615190 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL540500 0.98 TSHR (0.33) TSHRTHRB
SCHEMBL15260490 0.98 TSHR (0.30) TSHRTHRB
SCHEMBL21522634 0.96 TSHR (0.32) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8017687-B2 Swollen silicone composition and process of producing same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-09-13 US claimed
EP-2228053-A1 Swollen silicone composition and process of producing same Momentive Performance Materials Inc. (US) 2010-09-15 EP claimed
JP-2010515566-A 2010-05-13 JP claimed
EP-2108028-A2 METHOD OF APPLYING A COMPOSITION Momentive Performance Materials Inc. (US) 2009-10-14 EP claimed
JP-2009516024-A 2009-04-16 JP claimed
EP-1968533-A1 SWOLLEN SILICONE COMPOSITION AND PROCESS OF PRODUCING SAME Momentive Performance Materials Inc. (US) 2008-09-17 EP claimed
EP-1962791-A1 SWOLLEN SILICONE COMPOSITION, PROCESS OF PRODUCING SAME AND PRODUCTS THEREOF Momentive Performance Materials Inc. (US) 2008-09-03 EP claimed
WO-2008088323-A2 METHOD OF APPLYING A COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-24 WO claimed
US-20070160547-A1 Method of applying a composition MOMENTIVE PERFORMANCE MATERIALS INC. 2007-07-12 US claimed
WO-2007061623-A1 SWOLLEN SILICONE COMPOSITION, PROCESS OF PRODUCING SAME AND PRODUCTS THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-05-31 WO claimed
WO-2007058825-A1 SWOLLEN SILICONE COMPOSITION AND PROCESS OF PRODUCING SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-05-24 WO claimed
US-20070112146-A1 Swollen silicone composition, process of producing same and products thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2007-05-17 US claimed
US-20070112112-A1 Swollen silicone composition and process of producing same MOMENTIVE PERFORMANCE MATERIALS INC. 2007-05-17 US claimed
EP-1632269-A1 Cosmetic composition comprising a defined polymeric silicon and a surfactant L'OREAL (FR) 2006-03-08 EP claimed
EP-1621230-A1 Cosmetic composition comprising a defined polymeric silicone and a gelling agent L'OREAL (FR) 2006-02-01 EP claimed
EP-3768762-B1 SILICONE POLYMER MOMENTIVE PERFORMANCE MAT INC (US) 2025-02-19 EP disclosed
US-11472925-B2 Silicone polymer MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-18 US disclosed
WO-2003061612-A1 COMPOSITION CONTAINING A SEMI-CRYSTALLINE POLYMER AND A VOLATILE OIL L'OREAL (FR) 2003-07-31 WO disclosed
EP-1173139-A1 TRANSFER-RESISTANT COMPOSITION STRUCTURED IN RIGID FORM BY A POLYMER L'OREAL (FR) 2002-01-23 EP disclosed
WO-2001052799-A1 TRANSFER-RESISTANT COMPOSITION STRUCTURED IN RIGID FORM BY A POLYMER L'OREAL (FR) 2001-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472925-B2 Silicone polymer ZYX, ALG3, SPIN3 TSHR 4130/4885THRB 2869/4885
US-20070112146-A1 Swollen silicone composition, process of producing same and products thereof PIEZO1, SMS, ALG3 TSHR 4427/4885THRB 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.