Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254863 | 0.91 | TSHR (0.47) | CYP3A4TSHRATMTDP1NAAA | |
| SCHEMBL3628331 | 0.83 | TSHR (0.52) | CYP3A4TSHRATMTDP1NAAA | |
| SCHEMBL14191352 | 0.83 | TSHR (0.52) | CYP3A4TSHRATMTDP1NAAA | |
| SCHEMBL23049568 | 0.82 | PRKCA (0.51) | CYP3A4TSHRATMTDP1NAAA | |
| SCHEMBL3503949 | 0.82 | CYP3A4 (0.41) | CYP3A4TSHRATMTDP1NAAA | |
| SCHEMBL1408649 | 0.79 | KDM4E (0.61) | NAAAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9756806 | 0.79 | PRKCA (0.39) | TSHRNAAAKDM4EDUSP3MEN1 | |
| SCHEMBL374426 | 0.79 | LMNA (0.39) | NAAAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL23049638 | 0.79 | ALDH1A1 (0.44) | CYP3A4TSHRATMTDP1NAAA | |
| SCHEMBL12572610 | 0.79 | KDM4E (0.61) | NAAAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171223-B | Sulfur-containing silanes, filled elastomer compositions containing same, and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-04-20 | — | — | CN | disclosed |
| EP-2310397-B1 | SULFUR-CONTAINING SILANE, FILLED ELASTOMERIC COMPOSITIONS CONTAINING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-12-12 | — | — | EP | disclosed |
| CN-102171223-A | Sulfur-containing silanes, filled elastomer compositions containing same, and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2011-08-31 | — | — | CN | disclosed |
| EP-2310397-A1 | SULFUR-CONTAINING SILANE, FILLED ELASTOMERIC COMPOSITIONS CONTAINING SAME AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2011-04-20 | — | — | EP | disclosed |
| US-20110021692-A1 | Sulfur-Containing Silane, Filled Elastomeric Compositions Containing Same And Articles Made Therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-01-27 | — | — | US | disclosed |
| US-7786200-B2 | Sulfur-containing silane, filled elastomeric compositions containing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100029817-A1 | Sulfur-containing silane, filled elastomeric compositions containing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-04 | — | — | US | disclosed |
| WO-2010014238-A1 | SULFUR-CONTAINING SILANE, FILLED ELASTOMERIC COMPOSITIONS CONTAINING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-02-04 | — | — | WO | disclosed |