SCHEMBL374426

SCHEMBL374426

CCC(=O)OCC([O])CO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
DUSP3 P51452 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NAAA Q02083 1/20 0.39
PRKCA P17252 4/20 0.37
PRKCE Q02156 1/20 0.37
PRKCQ Q04759 1/20 0.37
PRKCD Q05655 1/20 0.37
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
WRN Q14191 1/20 0.35
HIF1A Q16665 1/20 0.35
TRPA1 O75762 1/20 0.34
DGKA P23743 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11662940 0.83 LMNA (0.49) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL1002145 0.79 CYP3A4 (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL9756907 0.78 NAAA (0.43) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL9756817 0.77 PRKCA (0.39) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL1408649 0.77 KDM4E (0.61) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL12572610 0.77 KDM4E (0.61) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL9756806 0.77 PRKCA (0.39) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL10551789 0.76
SCHEMBL7976838 0.76
SCHEMBL2254863 0.76 TSHR (0.47) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3241829-B1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2020-12-23 EP claimed
EP-2921485-B1 ISOXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP claimed
EP-2921484-B1 OXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP claimed
EP-2921495-B1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES BAYER IP GMBH (DE) 2018-03-28 EP claimed
EP-3013821-B1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2018-03-14 EP claimed
EP-2997008-B1 PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES OF OMARIGLIPTIN ITALIANA SINT SPA (IT) 2016-06-29 EP claimed
EP-2493571-B1 ALKYNYL DERIVATIVES USEFUL AS DPP-1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2014-07-23 EP claimed
EP-1874770-B1 PHENYLACETAMIDES SUITABLE AS PROTEIN KINASE INHIBITORS NOVARTIS AG (CH) 2011-03-09 EP claimed
EP-0836595-B1 TRIAZOLINE AND ISOXAZOLINE BIS-OXIME DERIVATIVES AND THEIR USE AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2004-01-02 EP claimed
US-10927319-B2 Use of a mixture of a complex ester with a monocarboxylic acid to reduce friction BASF SE (DE) 2021-02-23 US disclosed
US-20190345402-A1 USE OF A MIXTURE OF A COMPLEX ESTER WITH A MONOCARBOXYLIC ACID TO REDUCE FRICTION BASF SE (DE) 2019-11-14 US disclosed
US-10465138-B2 Use of a complex ester to reduce fuel consumption BASF SE (DE) 2019-11-05 US disclosed
EP-3559173-A1 USE OF A MIXTURE OF A COMPLEX ESTER WITH A MONOCARBOXYLIC ACID TO REDUCE FRICTION BASF SE (DE) 2019-10-30 EP disclosed
US-20180305631-A1 USE OF A COMPLEX ESTER TO REDUCE FUEL CONSUMPTION BASF SE (DE) 2018-10-25 US disclosed
US-4224315-A Pseudotrisaccharides and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1980-09-23 US disclosed
US-4221788-A 2-(Optionally-substituted)benzylperhydroazepines for analgesia and lowering blood pressure BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-09-09 US disclosed
US-4219552-A AND HAVING GOOD COCCIDIOSTATIC ACTION BAYER AKTIENGESELLSCHAFT (DE) 1980-08-26 US disclosed
US-4188395-A 1,4-Dihydropyridine derivatives substituted in the 2 position, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1980-02-12 US disclosed
US-4177278-A 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1979-12-04 US disclosed
EP-0000889-A1 3\"-N-Demethyl-3\"-N-substituted-4,6-di-0-(aminoglycosyl)-1,3-diaminocyclitols, methods for their preparation and their application as antibiotics BAYER AG (DE) 1979-03-07 EP disclosed