Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KAT7 | O95251 | 4/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.48 |
| ▸ | KAT6B | Q8WYB5 | 3/20 | 0.48 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053919 | 0.82 | MEN1 (0.50) | L3MBTL1KAT7KAT6AKAT6BKAT5 | |
| SCHEMBL10066968 | 0.81 | KMT2A (0.56) | L3MBTL1KAT7KAT6AKAT6BKAT5 | |
| SCHEMBL21392835 | 0.79 | CYP19A1 (0.46) | L3MBTL1KAT7KAT6AKAT6BKAT5 | |
| SCHEMBL4345848 | 0.78 | KMT2A (0.54) | L3MBTL1KAT7KAT6AKAT6BKAT5 | |
| SCHEMBL28853149 | 0.78 | ADRB2 (0.54) | L3MBTL1KAT7KAT6AKAT6BKMT2A | |
| SCHEMBL9886091 | 0.74 | TAAR1 (0.49) | ALDH1A1SMN1; SMN2TACR1 | |
| SCHEMBL29008820 | 0.73 | KDM4E (0.52) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31172576 | 0.73 | HTR2A (0.46) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL12278150 | 0.73 | GAA (0.59) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL10022374 | 0.73 | HTT (0.55) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165322-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165322-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165322-A1 | RHO KINASE INHIBITORS | ROCK1, ROCK2, RHOA | L3MBTL1 4323/4885KAT7 2219/4885KAT6A 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.