Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681405 | 0.92 | EGFR (0.46) | ALDH1A1CYP3A4HSD17B10EGFRCASP1 | |
| SCHEMBL30676613 | 0.92 | EGFR (0.46) | ALDH1A1CYP3A4HSD17B10EGFRCASP1 | |
| SCHEMBL10976089 | 0.78 | CYP2A6 (0.50) | TP53CDC7CDK2GRM4 | |
| SCHEMBL31259166 | 0.78 | PDPK1 (0.61) | ALDH1A1CYP3A4HSD17B10EGFRCASP1 | |
| SCHEMBL9939593 | 0.76 | PDPK1 (0.52) | EGFRPDPK1CDC7CDK2PIK3CD | |
| SCHEMBL24207389 | 0.75 | CYP2A6 (0.57) | ALDH1A1CYP3A4HSD17B10EGFRCASP1 | |
| SCHEMBL17374951 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HSD17B10EGFRCASP1 | |
| SCHEMBL933672 | 0.75 | CYP2A6 (0.46) | ALDH1A1CYP3A4EGFRMAPTKDM4E | |
| SCHEMBL10978740 | 0.75 | L3MBTL1 (0.50) | ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL17336629 | 0.75 | NOS1 (0.38) | CYP3A4MAPTSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354879-A | Benzamide derivative and application thereof | 中国药科大学 | 2023-06-30 | — | — | CN | disclosed |
| WO-2012020036-A1 | HEPATITIS C VIRUS INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-02-16 | — | — | WO | disclosed |
| US-20120039847-A1 | Hepatitis C Virus Inhibitors | ZHAO SHU-HAI (CN) | 2012-02-16 | — | — | US | disclosed |
| US-20120039847-A1 | Hepatitis C Virus Inhibitors | ZHAO SHU-HAI (CN) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039847-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, LIPC | ALDH1A1 802/4885CYP3A4 516/4885HSD17B10 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.