Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646552 | 0.84 | THRB (0.47) | MAPTTDP1KDM4EATML3MBTL1 | |
| SCHEMBL10025073 | 0.84 | MAPT (0.46) | MAPTTDP1KDM4EATML3MBTL1 | |
| SCHEMBL288157 | 0.83 | ALDH1A1 (0.52) | MAPTTDP1KDM4EATML3MBTL1 | |
| SCHEMBL6895096 | 0.83 | MAPT (0.44) | MAPTTDP1KDM4EATML3MBTL1 | |
| SCHEMBL322125 | 0.83 | MAPT (0.44) | MAPTTDP1KDM4EATML3MBTL1 | |
| Ethylene Glycol SCHEMBL7067335 | 0.82 | ALDH1A1 (0.48) | MAPTTDP1KDM4EATML3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27467368 | 0.82 | ALDH1A1 (0.50) | MAPTTDP1KDM4EATML3MBTL1 | |
| SCHEMBL4389489 | 0.81 | HSD17B10 (0.55) | MAPTTDP1KDM4EALOX15HSD17B10 | |
| SCHEMBL9241160 | 0.81 | TDP1 (0.54) | MAPTTDP1KDM4EATML3MBTL1 | |
| SCHEMBL18073 | 0.81 | TDP1 (0.54) | MAPTTDP1KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179378-A1 | Copolycarbonate Compositions with Cyclic and Linear Oligomers and Improved Optical Properties | COVESTRO DEUTSCHLAND AG (DE) | 2018-06-28 | — | — | US | disclosed |
| US-9969879-B2 | Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties | COVESTRO DEUTSCHLAND AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20170226340-A1 | Copolycarbonate Compositions with Branch Structures and Linear Oligomers and Improved Rheological Properties | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170218197-A1 | COPOLYCARBONATE COMPOSITIONS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-03 | — | — | US | disclosed |
| US-8455451-B2 | 2'-fluoro substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8158745-B2 | Polycarbonates having rearrangement structures, cyclic and linear oligomers and also flow behavior | BAYER MATERIALSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20110040066-A1 | POLYCARBONATES HAVING REARRANGEMENT STRUCTURES, CYCLIC AND LINEAR OLIGOMERS AND ALSO FLOW BEHAVIOR | BAYER MATERIALSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | PNP, NSUN2, CDA | MAPT 4506/4885TDP1 944/4885KDM4E 2598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.