SCHEMBL8646552

SCHEMBL8646552

O=C(OCCOC(=O)Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
ATM Q13315 2/20 0.45
ALOX15 P16050 2/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
PKM P14618 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28670261 0.94 THRB (0.43) THRBNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL6754012 0.94 THRB (0.43) THRBNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL6751546 0.94 THRB (0.43) THRBNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL5622652 0.90 TSHR (0.55) THRBNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL5696666 0.90 HCAR2 (0.53) NPC1RAB9ASMN1; SMN2TSHRTDP1
SCHEMBL8069407 0.90 MAPT (0.42) THRBNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL16814873 0.90 TDP1 (0.52) TSHRTDP1L3MBTL1ALDH1A1
SCHEMBL288157 0.90 ALDH1A1 (0.52) THRBTDP1MAPTKDM4EL3MBTL1
SCHEMBL321480 0.88 ALDH1A1 (0.41) THRBTDP1MAPTKDM4EL3MBTL1
SCHEMBL575071 0.88 MAPT (0.41) THRBTDP1MAPTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US disclosed
US-20240161778-A1 MAGNETIC RECORDING MEDIUM AND CARTRIDGE Sony Group Corporation (JP) 2024-05-16 US disclosed
US-11804243-B2 Magnetic recording medium Sony Group Corporation (JP) 2023-10-31 US disclosed
US-20230343365-A1 MAGNETIC RECORDING MEDIUM Sony Group Corporation (JP) 2023-10-26 US disclosed
US-20230317109-A1 MAGNETIC RECORDING MEDIUM AND CARTRIDGE Sony Group Corporation (JP) 2023-10-05 US disclosed
US-11749304-B2 Magnetic recording medium having controlled dimensional variation SONY CORPORATION (JP) 2023-09-05 US disclosed
US-11676631-B2 Magnetic recording medium and cartridge Sony Group Corporation (JP) 2023-06-13 US disclosed
US-20220396011-A1 RELEASE FILM AND METHOD FOR MANUFACTURING RELEASE FILM KOBAYASHI & CO., LTD. (JP) 2022-12-15 US disclosed
US-11521650-B2 Magnetic recording medium having a controlled dimensional variation SONY CORPORATION (JP) 2022-12-06 US disclosed
US-20220230660-A1 MAGNETIC RECORDING MEDIUM HAVING CONTROLLED DIMENSIONAL VARIATION SONY CORPORATION (JP) 2022-07-21 US disclosed
US-20170346136-A1 ELECTROLYTE AND LITHIUM-ION BATTERY CONTAINING THE SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2017-11-30 US disclosed
EP-2507268-B1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE GRACE W R & CO (US) 2014-10-15 EP disclosed
US-20130245306-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-09-19 US disclosed
US-20130245306-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-09-19 US disclosed
US-8263520-B2 Two atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture DOW GLOBAL TECHNOLOGIES LLC (US) 2012-09-11 US disclosed
US-8263520-B2 Two atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture DOW GLOBAL TECHNOLOGIES LLC (US) 2012-09-11 US disclosed
WO-2011068770-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO disclosed
US-20110130530-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-02 US disclosed
US-20110130530-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-02 US disclosed
US-5814394-A BLEND OF MAGNETIC POWDER AND BINDER KAO CORPORATION (JP) 1998-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130530-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE XRN2, TERF2, RAD52 THRB 2750/4885NPC1 2609/4885RAB9A 4602/4885
US-20130245306-A1 TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE HPD, TERT, DDT THRB 4469/4885NPC1 2123/4885RAB9A 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.