SCHEMBL288157

SCHEMBL288157

O=C(OCCO)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
RECQL P46063 1/20 0.52
GAA P10253 1/20 0.44
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
ATM Q13315 2/20 0.41
ALOX15 P16050 2/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
PKM P14618 1/20 0.40
CYP19A1 P11511 1/20 0.40
THRB P10828 1/20 0.40
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
GFER P55789 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27467368 0.98 ALDH1A1 (0.50) ALDH1A1RECQLGAAMAPTTDP1
SCHEMBL8646552 0.90 THRB (0.47) ALDH1A1MAPTTDP1KDM4EL3MBTL1
SCHEMBL10960942 0.89 TDP1 (0.44) ALDH1A1RECQLGAAMAPTTDP1
SCHEMBL9857105 0.87 TDP1 (0.47) ALDH1A1RECQLMAPTTDP1KDM4E
SCHEMBL321480 0.86 ALDH1A1 (0.41) ALDH1A1RECQLMAPTTDP1KDM4E
SCHEMBL6754012 0.84 THRB (0.43) ALDH1A1MAPTTDP1KDM4EL3MBTL1
SCHEMBL8069407 0.84 MAPT (0.42) ALDH1A1MAPTTDP1KDM4EL3MBTL1
SCHEMBL16814873 0.84 TDP1 (0.52) ALDH1A1TDP1L3MBTL1
SCHEMBL28670261 0.84 THRB (0.43) ALDH1A1MAPTTDP1KDM4EL3MBTL1
SCHEMBL6751546 0.84 THRB (0.43) ALDH1A1MAPTTDP1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4082729-A PROCESS FOR THE PREPARATION OF OXYMETHYLENE POLYMERS HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed
JP-9263630-A None JP disclosed
EP-2427049-B1 SURFACTANTS IN AGROCHEMICAL FORMULATIONS CRODA INC (US) 2020-03-18 EP disclosed
EP-2691402-B1 BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES ATLANTHERA (FR) 2019-05-08 EP disclosed
CN-107207924-A Adverse circumstances label assembly 艾利丹尼森公司 2017-09-26 CN disclosed
CN-106951950-A A kind of electronic license plate label of anti-conducting objects interference 华大半导体有限公司 2017-07-14 CN disclosed
US-9173946-B2 Bifunctional hydroxy-bisphosphonic acid derivatives ATLANTHERA (FR) 2015-11-03 US disclosed
US-9173946-B2 Bifunctional hydroxy-bisphosphonic acid derivatives ATLANTHERA (FR) 2015-11-03 US disclosed
US-20140086843-A1 BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES ATLANTHERA (FR) 2014-03-27 US disclosed
US-20140086843-A1 BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES ATLANTHERA (FR) 2014-03-27 US disclosed
EP-0735110-B1 Dye mixtures containing a hydroxypyridone azo dye DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-07-12 EP disclosed
JP-H09263630-A MODIFIED POLYCARBONATE BAYER AG 1997-10-07 JP disclosed
EP-0735110-A1 Dye mixtures containing a hydroxypyridone azo dye DyStar Japan Ltd. (JP) 1996-10-02 EP disclosed
EP-0232623-B1 1-CARBACEPHALOSPORIN ANTIBIOTICS ELI LILLY AND COMPANY (US) 1993-03-17 EP disclosed
US-4892942-A 1-CARBA (DETHIA)CEPHALOSPORINS ELI LILLY AND COMPANY (US) 1990-01-09 US disclosed
US-4791106-A 1-Carbacephalosporin antibiotics ELI LILLY AND COMPANY (US) 1988-12-13 US disclosed
EP-0232623-A1 1-Carbacephalosporin antibiotics ELI LILLY AND COMPANY (US) 1987-08-19 EP disclosed
US-4536512-A 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2,3-dihydro-1H-pyrrolizine-1-alkanoic or carboxylic acids and use thereof as anti-inflammatory and analgesic agents MERCK & CO., INC. (US) 1985-08-20 US disclosed
US-4533671-A 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2-alkanoic or carboxylic acids and analogs as anti-inflammatory and analgesic agents MERCK & CO., INC. (US) 1985-08-06 US disclosed
US-4082729-A PROCESS FOR THE PREPARATION OF OXYMETHYLENE POLYMERS HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140086843-A1 BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES BPGM, PHPT1, PTH1R ALDH1A1 1914/4885RECQL 3326/4885GAA 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.