Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13477776 | 0.92 | PDE4A (0.53) | PDE4AABCG2ABCB1MAPTTSHR | |
| SCHEMBL514651 | 0.91 | PDE4A (0.60) | PDE4AABCG2ABCB1MAPTTSHR | |
| SCHEMBL12937509 | 0.79 | KDM4E (0.69) | PDE4AMAPTTSHRMEN1KMT2A | |
| SCHEMBL14515226 | 0.79 | CSNK2A2 (0.53) | ABCG2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29493070 | 0.77 | ALOX5 (0.55) | ABCG2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5485044 | 0.77 | ALOX5 (0.55) | ABCG2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13955872 | 0.77 | PDE4A (0.60) | PDE4AABCG2ABCB1MAPTTSHR | |
| SCHEMBL9238940 | 0.76 | TUBB4A (0.52) | ABCG2ABCB1MAPTMEN1KMT2A | |
| SCHEMBL12937483 | 0.75 | PDE4A (0.44) | PDE4AMAPTTSHRMEN1KMT2A | |
| SCHEMBL15342384 | 0.74 | PDGFRB (0.57) | PDE4AMAPTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029216-A1 | SCALABLE SYNTHETIC PROCESS FOR MAKING TERAMEPROCOL | ERIMOS PHARMACEUTICALS LLC (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029216-A1 | SCALABLE SYNTHETIC PROCESS FOR MAKING TERAMEPROCOL | PTGIS, PTGES, POR | PDE4A 1354/4885ABCG2 1233/4885ABCB1 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.