SCHEMBL10028208

SCHEMBL10028208

c1ccc(-c2ccc3oc4c5c6c(oc7c-5c3c2c2ccccc72)c(-c2ccc3c5ccccc5c5oc7ccc(-c8ccccc8)c8c9ccccc9c9oc2c3c5-c9c78)ccc6c2ccccc42)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC14B O60729 2/20 0.36
CDC14A Q9UNH5 2/20 0.36
CYP1B1 Q16678 3/20 0.33
CYP1A1 P04798 3/20 0.33
CYP1A2 P05177 3/20 0.33
ALOX5 P09917 2/20 0.33
CDC25A P30304 2/20 0.33
CDC25C P30307 2/20 0.33
ARSA P15289 1/20 0.33
CDC25B P30305 1/20 0.33
CTRC Q99895 1/20 0.33
CYP19A1 P11511 2/20 0.32
CYP17A1 P05093 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
MEN1 O00255 1/20 0.31
CSF1R P07333 1/20 0.31
PDGFRB P09619 1/20 0.31
MAPT P10636 1/20 0.31
KIT P10721 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028163 0.87 CDC14B (0.38) CDC14BCDC14ACYP1B1CYP1A1CYP1A2
SCHEMBL10028209 0.84 ALOX5 (0.43) CDC14BCDC14ACYP1A2ALOX5CDC25A
SCHEMBL10028210 0.83 ARSA (0.38) CYP1A2ALOX5CDC25ACDC25CARSA
SCHEMBL12698548 0.76 CTRC (0.42) CDC14BCDC14ACYP1B1CYP1A1CYP1A2
SCHEMBL10028166 0.76 GPR84 (0.36) CDC14BCDC14ACYP1B1CTRCCYP19A1
SCHEMBL10028165 0.75 ARSA (0.43) CYP1A2ALOX5CDC25ACDC25CARSA
SCHEMBL14476534 0.72 PRKDC (0.40) CDC14BCDC14ACYP1A2ALOX5CDC25A
SCHEMBL10028155 0.72 CA1 (0.37) CDC14BCDC14ACYP1B1CYP1A1CYP1A2
SCHEMBL10650956 0.72 ALOX5 (0.44) CDC14BCDC14ACYP1B1CYP1A1CYP1A2
SCHEMBL10028164 0.72 GPR84 (0.44) CYP1B1CYP1A1CYP1A2ALOX5CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, SOD1, SLC40A1 CDC14B 4744/4885CDC14A 4708/4885CYP1B1 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.