Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023092 | 0.85 | PLAU (0.45) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL9572324 | 0.83 | PLAU (0.59) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL28574517 | 0.83 | PLAU (0.59) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL27609200 | 0.79 | ESR1 (0.58) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL4670540 | 0.79 | ESR1 (0.58) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL15274959 | 0.79 | PLAU (0.40) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL2445157 | 0.78 | ALDH1A1 (0.57) | PLAUCYP3A4CTDSP1NSD2DUSP3 | |
| SCHEMBL8777376 | 0.77 | HSD17B1 (0.56) | CYP3A4CYP2C9CYP2C19HSD17B1HSD17B2 | |
| SCHEMBL8121539 | 0.76 | ALDH1A1 (0.55) | PLAUCYP3A4CTDSP1NSD2DUSP3 | |
| SCHEMBL3871771 | 0.75 | KDM4E (0.52) | PLAUCYP3A4CYP2C9CYP2C19HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SOD1, SLC40A1 | PLAU 3665/4885CYP3A4 1649/4885CYP2C9 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.