Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907494 | 0.87 | KMT2A (0.36) | KMT2ALMNAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9899997 | 0.79 | CYP1A2 (0.42) | KMT2ALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL8907501 | 0.74 | MAPT (0.39) | KMT2ACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL311625 | 0.73 | CYP1A2 (0.46) | KMT2ALMNAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL311624 | 0.73 | CYP1A2 (0.46) | KMT2ALMNAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL7432714 | 0.72 | CYP1A2 (0.44) | KMT2ALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL14423555 | 0.72 | CYP1A2 (0.44) | KMT2ALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL16576907 | 0.72 | MAPT (0.37) | KMT2AHTTMAPTALDH1A1NPC1 | |
| SCHEMBL24966945 | 0.72 | ALDH1A1 (0.47) | KMT2ALMNAHTTCYP1A2CYP2C9 | |
| SCHEMBL14843091 | 0.70 | GABRA1 (0.32) | GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106230-B2 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20100076203-A1 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076203-A1 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | SUCNR1, DLST, SHMT2 | KMT2A 277/4885LMNA 2588/4885HTT 736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.