SCHEMBL10029692

SCHEMBL10029692

O=C(c1cccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1)c1cccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
ALDH1A1 P00352 2/20 0.52
PBRM1 Q86U86 1/20 0.52
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SRD5A2 P31213 1/20 0.45
MAPT P10636 2/20 0.44
PTGS1 P23219 2/20 0.44
CXCR1 P25024 2/20 0.44
CXCR2 P25025 2/20 0.44
PTGS2 P35354 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
RECQL P46063 1/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10476991 0.88 KMO (0.53) ATMTDP1L3MBTL1SRD5A2KDM4E
SCHEMBL17952447 0.85 L3MBTL1 (0.50) ATMTDP1L3MBTL1ALDH1A1PBRM1
SCHEMBL28678908 0.83 CA12 (0.56) HPGDHSD17B10CA1CA2
SCHEMBL30600553 0.81 ATM (0.39) ATMTDP1L3MBTL1ALDH1A1PBRM1
SCHEMBL29088255 0.81 ATM (0.39) ATMTDP1L3MBTL1ALDH1A1PBRM1
SCHEMBL13703264 0.80 ALDH1A1 (0.67) ATMTDP1L3MBTL1ALDH1A1PBRM1
SCHEMBL10029706 0.80 ALDH1A1 (0.59) ATMTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL17952444 0.78 L3MBTL1 (0.55) ATMTDP1L3MBTL1ALDH1A1PBRM1
SCHEMBL135162 0.77 ATM (1.00) ATMTDP1L3MBTL1ALDH1A1PBRM1
SCHEMBL9324919 0.77 ATM (1.00) ATMTDP1L3MBTL1ALDH1A1PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed