SCHEMBL29088255

SCHEMBL29088255

C=C(C(=O)O)c1cccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ACHE P22303 1/20 0.37
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
TSHR P16473 2/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMO O15229 1/20 0.35
AKT1 P31749 1/20 0.34
MAPT P10636 2/20 0.34
PBRM1 Q86U86 1/20 0.34
KCNK3 O14649 1/20 0.34
KCNK9 Q9NPC2 1/20 0.34
LMNA P02545 1/20 0.34
XBP1 P17861 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30600553 1.00 ATM (0.39) ATMTDP1L3MBTL1ACHECES2
SCHEMBL29072538 0.83 CES2 (0.38) ATMTDP1CES2CES1TSHR
SCHEMBL10029692 0.81 ATM (0.61) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL10476991 0.81 KMO (0.53) ATMTDP1L3MBTL1CES2CES1
SCHEMBL271385 0.80 L3MBTL1 (0.52) ATMTDP1L3MBTL1CES2CES1
SCHEMBL28678908 0.77 CA12 (0.56) TSHRDAONAPRTKMOHSD17B10
SCHEMBL44226 0.76 CES1 (0.52) ATMTDP1L3MBTL1CES2CES1
SCHEMBL4804883 0.76 KMO (0.62) TDP1KMOMAPTERCC5FEN1
SCHEMBL4735624 0.76 ATM (0.72) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL9419398 0.74 TDP1 (0.52) ATMTDP1L3MBTL1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116896909-A Heterocyclic compound, light-emitting element including the same, and electronic device 三星显示有限公司 2023-10-17 CN disclosed