SCHEMBL10029706

SCHEMBL10029706

O=C(c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1)c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
SRD5A2 P31213 4/20 0.56
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
RAB9A P51151 4/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
MAPK13 O15264 1/20 0.48
MAPK12 P53778 1/20 0.48
MAPK11 Q15759 1/20 0.48
MAPK14 Q16539 1/20 0.48
NPC1 O15118 3/20 0.47
HPGD P15428 2/20 0.47
ELANE P08246 2/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13703264 0.95 ALDH1A1 (0.67) ALDH1A1SRD5A2MEN1KMT2AL3MBTL1
SCHEMBL2197326 0.86 TSHR (0.59) ALDH1A1SRD5A2RAB9ANPC1HPGD
SCHEMBL10476977 0.86 TSHR (0.59) ALDH1A1SRD5A2RAB9ANPC1HPGD
SCHEMBL17952443 0.85 RAB9A (0.53) ALDH1A1SRD5A2MEN1KMT2AL3MBTL1
SCHEMBL8535872 0.82 CES2 (0.41) ALDH1A1SRD5A2L3MBTL1TDP1MAPT
SCHEMBL14520966 0.81 KMT2A (0.49) ALDH1A1SRD5A2MEN1KMT2AL3MBTL1
SCHEMBL10029692 0.80 ATM (0.61) ALDH1A1SRD5A2MEN1KMT2AL3MBTL1
SCHEMBL9066312 0.79 ALDH1A1 (0.93) ALDH1A1SRD5A2MEN1KMT2AL3MBTL1
SCHEMBL314267 0.79 ALDH1A1 (0.93) ALDH1A1SRD5A2MEN1KMT2AL3MBTL1
SCHEMBL103830 0.79 ESR1 (0.43) ALDH1A1MEN1KMT2ATDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed