SCHEMBL2197326

SCHEMBL2197326

O=C(O)c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
NAPRT Q6XQN6 2/20 0.59
DAO P14920 1/20 0.59
HPGD P15428 1/20 0.58
TP53 P04637 1/20 0.57
SRD5A2 P31213 4/20 0.56
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
TRPA1 O75762 1/20 0.50
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
TYR P14679 1/20 0.48
DRD1 P21728 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10476977 1.00 TSHR (0.59) TSHRNAPRTDAOHPGDTP53
SCHEMBL16749651 0.93 TSHR (0.67) TSHRNAPRTDAOHPGDTP53
SCHEMBL16772175 0.86 BCL2L1 (0.58) TSHRHPGDTP53SRD5A2CA1
SCHEMBL10029706 0.86 ALDH1A1 (0.59) HPGDSRD5A2CES2CES1NPC1
SCHEMBL10476981 0.85 CA1 (0.69) HPGDCES2CES1CA1CA2
SCHEMBL8535872 0.82 CES2 (0.41) TSHRNAPRTDAOHPGDTP53
SCHEMBL30485900 0.82 HPGD (0.65) TSHRNAPRTDAOHPGDTP53
SCHEMBL13703264 0.81 ALDH1A1 (0.67) TSHRHPGDTP53SRD5A2CES2
SCHEMBL10476991 0.80 KMO (0.53) TSHRNAPRTDAOHPGDSRD5A2
SCHEMBL1931860 0.80 HPGD (0.63) TSHRNAPRTDAOHPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534836-A Polybenzoxazole precursor, process for producing the same, and photosensitive resin composition 上海交通大学 2024-02-09 CN claimed
CN-117534836-A Polybenzoxazole precursor, process for producing the same, and photosensitive resin composition 上海交通大学 2024-02-09 CN disclosed
WO-2023195202-A1 HYBRID BONDING INSULATION FILM-FORMING MATERIAL, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE HDマイクロシステムズ株式会社 2023-10-12 WO disclosed
US-20230221639-A1 PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR PRODUCING CURED RELIEF PATTERN ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-07-13 US disclosed
US-11640112-B2 Photosensitive resin composition and method for producing cured relief pattern ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-05-02 US disclosed
CN-110088680-B Double-layer photosensitive layer roll 旭化成株式会社 2022-12-30 CN disclosed
US-20220011669-A1 PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR PRODUCING CURED RELIEF PATTERN ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-01-13 US disclosed
US-11163234-B2 Photosensitive resin composition and method for producing cured relief pattern ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-02 US disclosed
US-11048167-B2 Positive photosensitive resin composition, patterned cured film production method, patterned cured film, and electronic component HD MICROSYSTEMS, LTD. (JP) 2021-06-29 US disclosed
US-11021572-B2 Photosensitive resin composition, cured product of same, interlayer insulating film, surface protective film and electronic component HD MICROSYSTEMS, LTD. (JP) 2021-06-01 US disclosed
EP-0387061-A2 Novel polyamide-polyamide and polybenzoxazole-polyamide polymers HOECHST CELANESE CORPORATION (US) 1990-09-12 EP disclosed
US-4939215-A CHEMICAL AND RADIATION RESISTANCE; AIRCRAFT, ELECTRONICS HOECHST CELANESE CORPORATION (US) 1990-07-03 US disclosed
US-4866155-A HEAT, RADIATION RESISTANCE; TRANSPARENCY HOECHST CELANESE CORPORATION (US) 1989-09-12 US disclosed
EP-0323561-A2 Polyesters of bis (2-(4-hydroxyphenyl) hexafluoroisopropyl)- diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-07-12 EP disclosed
US-4845183-A MOLDING MATERIALS; FOR DIELECTRICS OR COATING SOLUTIONS; TOUGHNESS, FLEXIBILITY, TRANSPARENT HOECHST CELANESE CORPORATION (US) 1989-07-04 US disclosed
EP-0317942-A2 Heat resistant polyamides and polybenzoxazoles from bis-[(aminohydroxyphenyl hexafluoro-isopropyl] diphenyl ethers HOECHST CELANESE CORPORATION (US) 1989-05-31 EP disclosed
EP-0317940-A2 Polycarbonamides of bis (2-(4-carboxyphenyl)hexafluoroisopropyl) - diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 EP disclosed
US-4822868-A Polycarbonamide of bis(2-(4-carboxyphenyl)-hexafluoroisopropyl)diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-04-18 US disclosed
US-4671957-A POVIDONE-IODINE FOR BURNS AND SKIN DISORDERS FUNGICIDES, VIRICIDES EUROCELTIQUE, S.A. (LU) 1987-06-09 US disclosed
EP-0185490-A2 Antibacterial cream Euroceltique S.A. (LU) 1986-06-25 EP disclosed