SCHEMBL10030014

SCHEMBL10030014

Cc1ccc2c(c1)nc(-c1ccc(-c3ccccc3)cc1)n2C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.61
HDAC1 Q13547 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
ACSS2 Q9NR19 1/20 0.57
ATM Q13315 1/20 0.56
PDE10A Q9Y233 2/20 0.54
ALDH1A1 P00352 4/20 0.54
PKM P14618 3/20 0.54
RAB9A P51151 3/20 0.54
KDM4E B2RXH2 3/20 0.54
NPC1 O15118 2/20 0.54
TP53 P04637 2/20 0.54
HSD17B10 Q99714 2/20 0.54
GAA P10253 1/20 0.54
ALOX15 P16050 1/20 0.54
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104834 0.97 NLRP3 (0.65) NLRP3HDAC1HDAC8HDAC6ACSS2
SCHEMBL1104828 0.90 HDAC1 (0.64) NLRP3HDAC1HDAC8HDAC6ATM
SCHEMBL16692131 0.84 HDAC1 (0.59) NLRP3HDAC1HDAC8HDAC6ATM
SCHEMBL1104822 0.83 ATM (0.55) NLRP3HDAC1HDAC8HDAC6ACSS2
SCHEMBL3752453 0.83 HDAC1 (0.57) HDAC1HDAC8HDAC6ATMPDE10A
SCHEMBL9611665 0.83 ALDH1A1 (0.75) HDAC1HDAC8HDAC6ATMALDH1A1
SCHEMBL10249140 0.82 MEN1 (0.66) NLRP3HDAC1HDAC8HDAC6ACSS2
SCHEMBL13098078 0.82 HDAC1 (0.56) NLRP3HDAC1HDAC8HDAC6ATM
SCHEMBL1104827 0.81 PDE10A (0.59) HDAC1HDAC8HDAC6ATMPDE10A
SCHEMBL15080534 0.81 CA12 (0.49) NLRP3HDAC1HDAC8HDAC6ACSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11189809-B2 Organic EL device and display unit SONY CORPORATION (JP) 2021-11-30 US disclosed
US-10411212-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-09-10 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9860960-B2 Organic EL display device and method for production of the same JOLED INC. (JP) 2018-01-02 US disclosed
US-20170271609-A1 ORGANIC EL DEVICE AND DISPLAY UNIT SONY CORPORATION (JP) 2017-09-21 US disclosed
US-20170271609-A1 ORGANIC EL DEVICE AND DISPLAY UNIT SONY CORPORATION (JP) 2017-09-21 US disclosed
US-9257663-B2 Organic electroluminescent element and display device SONY CORPORATION (JP) 2016-02-09 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-20120112173-A1 ORGANIC EL DISPLAY DEVICE AND METHOD FOR PRODUCTION OF THE SAME SONY CORPORATION (JP) 2012-05-10 US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20110024736-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY SONY CORPORATION (JP) 2011-02-03 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10411212-B2 Organic electroluminescent element L1CAM, NES, EML4 NLRP3 2715/4885HDAC1 2427/4885HDAC8 4514/4885
US-11189809-B2 Organic EL device and display unit L1CAM, ESR1, EPHA8 NLRP3 921/4885HDAC1 4213/4885HDAC8 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.