Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030483 | 0.86 | PAX8 (0.52) | TDP1MEN1KMT2AHTTPOLB | |
| SCHEMBL24565134 | 0.85 | TDP1 (0.57) | TDP1L3MBTL1KMT2ALMNAHTT | |
| SCHEMBL10030479 | 0.84 | RAB9A (0.42) | TDP1MEN1KMT2ALMNAHTT | |
| SCHEMBL17796023 | 0.83 | THRB (0.52) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL10030478 | 0.80 | HTT (0.39) | TDP1MEN1KMT2ALMNAHTT | |
| SCHEMBL10030486 | 0.80 | PAX8 (0.45) | TDP1LMNAFFAR1HTTPOLB | |
| SCHEMBL2360555 | 0.79 | THRB (0.53) | TDP1L3MBTL1LMNAHTTPOLB | |
| SCHEMBL65346 | 0.76 | TDP1 (0.52) | TDP1L3MBTL1KMT2ALMNAHTT | |
| SCHEMBL10030485 | 0.75 | POLB (0.40) | TDP1MEN1KMT2ALMNAFFAR1 | |
| SCHEMBL21400769 | 0.74 | TDP1 (0.43) | TDP1L3MBTL1LMNAFFAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | TERB1, H1-5, RRP15 | TDP1 2016/4885L3MBTL1 2158/4885MEN1 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.