Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661551 | 0.83 | CALM1 (0.56) | CALM1HDAC1HDAC2LMNAKMT2A | |
| SCHEMBL10030780 | 0.82 | TUBB4A (0.53) | CALM1LMNAKMT2ATUBB4ATUBB | |
| SCHEMBL10030783 | 0.81 | CALM1 (0.50) | CALM1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL10030792 | 0.81 | TUBB1 (0.47) | LMNAMAPTKMT2ATUBB4ATUBB | |
| SCHEMBL10030787 | 0.76 | TUBB4A (0.64) | LMNAKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL10030789 | 0.74 | GAA (0.51) | CALM1LMNAKMT2ATUBB4ATUBB | |
| SCHEMBL13991618 | 0.74 | TUBB4A (0.61) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10030785 | 0.74 | CALM1 (0.40) | CALM1HDAC1HDAC2KMT2ATSHR | |
| SCHEMBL13778143 | 0.72 | CYP1A1 (0.46) | APPTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145748 | 0.72 | MMP2 (0.44) | APPTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | Zhejiang Wild Wind Pharmaceutical Co., Ltd. (CN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | TUBB1, TUBB, TUBB3 | CALM1 3394/4885HDAC1 2376/4885HDAC2 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.