SCHEMBL10031

SCHEMBL10031

O=c1cc[nH]c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
CCR8 P51685 1/20 0.50
HSD17B10 Q99714 3/20 0.48
KMT2A Q03164 1/20 0.48
AHR P35869 2/20 0.46
TRPA1 O75762 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
ITGB2 P05107 1/20 0.46
ICAM1 P05362 1/20 0.46
ITGAL P20701 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
ADK P55263 1/20 0.46
KDM4E B2RXH2 4/20 0.46
CYP1A2 P05177 2/20 0.45
GAA P10253 2/20 0.45
PARP1 P09874 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6366012 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Hydrochloric Acid SCHEMBL3646722 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Benzene SCHEMBL28794130 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Fluoride SCHEMBL4741374 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
SCHEMBL20677769 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Hydrochloric Acid SCHEMBL3397919 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Hydrochloric Acid SCHEMBL29744420 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Iodide SCHEMBL7508631 0.98 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
SCHEMBL18900583 0.86 FKBP5 (0.44) ALDH1A1HSD17B10KMT2AAHRKDM4E
Fumaric Acid SCHEMBL4611816 0.85 HTR1A (0.47) ALDH1A1HSD17B10KMT2AAHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3912 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP claimed
US-20260014137-A1 METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS WAYNE STATE UNIVERSITY (US) 2026-01-15 US claimed
US-12509439-B2 Anti-malarial agents UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2025-12-30 US claimed
US-20250332117-A1 Thin Films with Peroxides and Uses Thereof Silverpeutics, Inc. (US) 2025-10-30 US claimed
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2025-07-01 US claimed
CN-116120227-B Preparation method of 4-quinolone derivative 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2025-02-28 CN claimed
WO-2025038572-A1 SN2 GLYCOSYLATION SUITABLE FOR AUTOMATED GLYCAN SYNTHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 WO claimed
EP-3464243-B1 AN IMPROVED PROCESS FOR THE SYNTHESIS OF IVACAFTOR COUNCIL SCIENT IND RES (IN) 2025-02-12 EP claimed
CN-119306697-A 4-Quinolinone derivative and preparation method and application thereof 山东大学 2025-01-14 CN claimed
CN-119013279-A Substituted tricyclic compounds as PARP inhibitors and uses thereof 上海瑛派药业有限公司 2024-11-22 CN claimed
EP-0104959-B1 4-QUINOLONE DERIVATIVES NIPPON SHINYAKU COMPANY, LIMITED (JP) 1987-01-21 EP claimed
EP-0206616-A2 Quinolones having antihypertensive activity The Boots Company PLC (GB) 1986-12-30 EP claimed
EP-0090769-B1 PROCESS FOR THE PREPARATION OF 1,2,5,6-TETRAHYDRO-4H-PYRROLO(3,2,1-IJ)-QUINOLIN-4-ONE AND 5-HALO-1,2,3-(1,2,DIHYDROPYRROLO)-4-QUINOLONE INTERMEDIATES CIBA-GEIGY AG (CH) 1986-08-20 EP claimed
US-4595755-A 5-halo-1,2,3-(1,2-dihydropyrrolo)-4-quinolones CIBA-GEIGY CORPORATION (US) 1986-06-17 US claimed
US-4518685-A BLOCKED AGENT FOR STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1985-05-21 US claimed
US-4508902-A OXIDATION OF 1,2,3,4-TETRAHYDROQUINOLINE-4-ONES RHONE-POULENC SANTE (FR) 1985-04-02 US claimed
EP-0125523-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-11-21 EP claimed
US-4421920-A AMINATION, AROMATIZATION, RUTHENIUM CATALYST RHONE-POULENC SANTE (FR) 1983-12-20 US claimed
EP-0000203-B1 1-ETHYL-7-CHLORO-6-FLUORO-4-QUINOLONE-3-CARBOXYLIC ACID, ITS PREPARATION AND APPLICATION AS PLANT BACTERICIDE CIBA-GEIGY AG (CH) 1981-07-01 EP claimed
US-3995040-A Cyclopenteno-3-carboxyl-4-quinolone derivatives and their bacteriostatic compositions BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-11-30 US claimed