Fluoride

Fluoride

SCHEMBL4741374

F.O=c1cc[nH]c2ccccc12

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
CCR8 P51685 1/20 0.48
HSD17B10 Q99714 3/20 0.47
KMT2A Q03164 1/20 0.46
AHR P35869 2/20 0.44
TRPA1 O75762 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
ITGB2 P05107 1/20 0.44
ICAM1 P05362 1/20 0.44
ITGAL P20701 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
ADK P55263 1/20 0.44
KDM4E B2RXH2 4/20 0.44
CYP1A2 P05177 2/20 0.44
GAA P10253 2/20 0.44
PARP1 P09874 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10031 0.98 ALDH1A1 (0.55) ALDH1A1CCR8HSD17B10KMT2AAHR
Hydrochloric Acid SCHEMBL3646722 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Hydrochloric Acid SCHEMBL29744420 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
SCHEMBL20677769 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Iodide SCHEMBL7508631 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Benzene SCHEMBL28794130 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
Hydrochloric Acid SCHEMBL3397919 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
SCHEMBL6366012 0.95 ALDH1A1 (0.53) ALDH1A1CCR8HSD17B10KMT2AAHR
SCHEMBL18900583 0.84 FKBP5 (0.44) ALDH1A1HSD17B10KMT2AAHRKDM4E
Fumaric Acid SCHEMBL4611816 0.83 HTR1A (0.47) ALDH1A1HSD17B10KMT2AAHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008096917-A1 REACTIVE ANTIBIOTICS AND ANTIBACTERIAL FIBER TREATED THEREBY KOLON INDUSTRIES, INC (KR) 2008-08-14 WO disclosed