SCHEMBL1003182

SCHEMBL1003182

CCCOC(OCCC)[SiH2]c1ccc(CCCl)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPL P06858 5/20 0.37
LIPG Q9Y5X9 5/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
TRPV1 Q8NER1 1/20 0.33
MGLL Q99685 1/20 0.33
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705704 0.84 LPL (0.30) LPLLIPG
SCHEMBL9804112 0.76 MAPT (0.36) LMNAL3MBTL1
SCHEMBL31094240 0.75 LMNA (0.36) LMNAL3MBTL1
SCHEMBL23493443 0.72 CHRNB2 (0.41)
SCHEMBL23493431 0.71 ALDH1A1 (0.30)
SCHEMBL11146575 0.68
SCHEMBL17529865 0.66 LMNA (0.33) LMNAL3MBTL1
SCHEMBL9860834 0.65 GFER (0.42) CA2L3MBTL1
SCHEMBL8995713 0.65 TSHR (0.41) CA1CA2LMNA
SCHEMBL21138387 0.64 TAAR1 (0.56) LPLLIPGCA2MGLLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863398-B2 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-04 US claimed
EP-2134767-B1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MAT INC (US) 2010-09-15 EP claimed
EP-2134767-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS Momentive Performance Materials Inc. (US) 2009-12-23 EP claimed
US-20080242825-A1 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US claimed
WO-2008118460-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-02 WO claimed
US-7863398-B2 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-04 US disclosed
EP-2134767-B1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MAT INC (US) 2010-09-15 EP disclosed
EP-2134767-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS Momentive Performance Materials Inc. (US) 2009-12-23 EP disclosed
US-20080242825-A1 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US disclosed
WO-2008118460-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-02 WO disclosed