SCHEMBL1003274

SCHEMBL1003274

CCO[Si](C)(C)CCCCCl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31714537 0.98 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL17669093 0.98 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL319534 0.98 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL56265 0.93 TSHR (0.35) TSHRALDH1A1TDP1
SCHEMBL706690 0.87
SCHEMBL13430609 0.85
SCHEMBL929338 0.85
SCHEMBL557561 0.85
SCHEMBL15177125 0.85
SCHEMBL55968 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432314-A Anti-yellowing and anti-aging single-component transparent sealant and preparation method thereof 广州白云科技股份有限公司 2025-02-14 CN claimed
CN-117924346-A Multi-sulfur-containing silane coupling agent and preparation method thereof 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
CN-103554168-B Epoxy radicals silicone hydride, its preparation method and the curable compositions comprising it 莫门蒂夫性能材料股份有限公司 2017-07-18 CN claimed
CN-101679624-B Process for preparing hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MAT INC 2012-07-04 CN claimed
US-7863398-B2 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-04 US claimed
EP-2134767-B1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MAT INC (US) 2010-09-15 EP claimed
CN-101679624-A Process for preparing hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MAT INC 2010-03-24 CN claimed
EP-2134767-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS Momentive Performance Materials Inc. (US) 2009-12-23 EP claimed
US-20080242825-A1 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US claimed
WO-2008118460-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-02 WO claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
CN-122010684-A Method for synthesizing methyl butenol through heterogeneous hydrogenation reaction 万华化学集团股份有限公司 2026-05-12 CN disclosed
CN-119432314-A Anti-yellowing and anti-aging single-component transparent sealant and preparation method thereof 广州白云科技股份有限公司 2025-02-14 CN disclosed
CN-118401567-A Silane-functional amine compositions and their use in rubber 迈图高新材料公司 2024-07-26 CN disclosed
WO-2004012874-A1 CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2004-02-12 WO disclosed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO disclosed
US-5905150-A HEATING IN PRESENCE OF PHASE TRANSFER AGENT GENERAL ELECTRIC COMPANY (US) 1999-05-18 US disclosed
EP-0900801-A1 Process for preparing organosilanes GENERAL ELECTRIC COMPANY (US) 1999-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 TSHR 2005/4885ALDH1A1 2127/4885TDP1 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.