Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033095 | 0.85 | L3MBTL1 (0.41) | ALDH1A1DPP4CACNA1FCACNA1DCACNA1S | |
| SCHEMBL10033131 | 0.84 | ALDH1A1 (0.42) | ALDH1A1DPP4KDM4ECACNA1FCACNA1D | |
| SCHEMBL10033106 | 0.82 | HTR2A (0.38) | ALDH1A1KDM4EKDM1A | |
| SCHEMBL10033113 | 0.80 | L3MBTL1 (0.42) | ALDH1A1KDM1A | |
| SCHEMBL10033104 | 0.79 | MEN1 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL10033130 | 0.76 | TACR1 (0.41) | ALDH1A1KDM4EKDM1ARCOR1 | |
| SCHEMBL10033098 | 0.76 | ALOX5AP (0.39) | ALDH1A1DPP4KDM4E | |
| SCHEMBL10033128 | 0.76 | ALOX5AP (0.36) | ALDH1A1DPP4KDM4EBRD4 | |
| SCHEMBL10033112 | 0.75 | BRD4 (0.42) | ALDH1A1KDM4EBCHEKDM1ARCOR1 | |
| SCHEMBL10033097 | 0.74 | KDM4E (0.39) | ALDH1A1MDM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |