Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033106 | 0.89 | HTR2A (0.38) | L3MBTL1ALDH1A1MEN1KMT2AALOX5AP | |
| SCHEMBL10033131 | 0.89 | ALDH1A1 (0.42) | L3MBTL1DPP4SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10033113 | 0.87 | L3MBTL1 (0.42) | L3MBTL1SMN1; SMN2ALDH1A1LMNASLC6A2 | |
| SCHEMBL10033101 | 0.85 | ALDH1A1 (0.40) | DPP4ALDH1A1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL10033104 | 0.84 | MEN1 (0.38) | L3MBTL1SMN1; SMN2NPSR1ALDH1A1LMNA | |
| SCHEMBL10033129 | 0.81 | PPOX (0.36) | L3MBTL1PPOXDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL10033130 | 0.79 | TACR1 (0.41) | NPSR1ALDH1A1ATM | |
| SCHEMBL10033098 | 0.79 | ALOX5AP (0.39) | L3MBTL1DPP4HPGDNPSR1ALDH1A1 | |
| SCHEMBL10033125 | 0.79 | GRIA4 (0.38) | NPSR1LMNAATM | |
| SCHEMBL10033100 | 0.79 | CYP11B1 (0.35) | L3MBTL1PPOXDPP4NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |