Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033184 | 0.92 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1GAAACACBHPGD | |
| SCHEMBL10033180 | 0.91 | SLC6A2 (0.34) | L3MBTL1SLC6A3SLC6A2SLC6A4HPGD | |
| SCHEMBL10033178 | 0.81 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL10033190 | 0.78 | L3MBTL1 (0.33) | L3MBTL1HPGDKCNK3PARP14 | |
| SCHEMBL10033131 | 0.76 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10032824 | 0.76 | GRIA4 (0.40) | MEN1KMT2A | |
| SCHEMBL10033189 | 0.74 | TACR1 (0.39) | ALDH1A1 | |
| SCHEMBL10033185 | 0.72 | RECQL (0.33) | L3MBTL1ALDH1A1GAASLC6A3SLC6A2 | |
| SCHEMBL10033182 | 0.71 | BRD4 (0.38) | L3MBTL1ALDH1A1GAASLC6A3SLC6A2 | |
| SCHEMBL10032830 | 0.71 | GRIA4 (0.41) | L3MBTL1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |