Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033120 | 0.93 | NPC1 (0.35) | PTGDR2FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL1709397 | 0.88 | ALDH1A1 (0.36) | PTGDR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10033118 | 0.88 | OPRL1 (0.38) | PTGDR2 | |
| SCHEMBL1709473 | 0.85 | ALDH1A1 (0.38) | PTGDR2HDAC1HDAC6NPC1GAA | |
| SCHEMBL1709406 | 0.84 | EPHX2 (0.32) | PTGDR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10032828 | 0.82 | ALDH1A1 (0.35) | PTGDR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1709359 | 0.80 | USP30 (0.38) | PTGDR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1709489 | 0.79 | OPRM1 (0.37) | PTGDR2PKMDGAT1 | |
| SCHEMBL1709399 | 0.79 | PTGDR (0.41) | PTGDR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1709409 | 0.78 | POLB (0.38) | PKMRAB9ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |