Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | CCR5 | P51681 | 9/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709407 | 0.88 | TP53 (0.39) | OPRM1OPRD1 | |
| SCHEMBL1709481 | 0.87 | MDM2 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL1709409 | 0.87 | POLB (0.38) | PKMSLC6A2SLC6A4DGAT1 | |
| SCHEMBL1709359 | 0.86 | USP30 (0.38) | PKMSLC6A2SLC6A4PTGDR2DGAT1 | |
| SCHEMBL1709459 | 0.83 | CXCR3 (0.34) | PKMSLC6A2SLC6A4 | |
| SCHEMBL1709358 | 0.83 | DPEP1 (0.36) | PKMSLC6A2SLC6A4DGAT1 | |
| SCHEMBL1709408 | 0.83 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL1709454 | 0.82 | SLC6A2 (0.40) | PKMSLC6A2SLC6A4 | |
| SCHEMBL1709473 | 0.81 | ALDH1A1 (0.38) | PKMSLC6A2SLC6A4PTGDR2 | |
| SCHEMBL1709480 | 0.80 | NPC1 (0.38) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |