Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033118 | 0.86 | OPRL1 (0.38) | EPHX2ALDH1A1PTGDR2 | |
| SCHEMBL1709473 | 0.86 | ALDH1A1 (0.38) | EPHX2SLC6A2SLC6A4ALDH1A1HDAC1 | |
| SCHEMBL10033119 | 0.84 | PTGDR2 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1709359 | 0.83 | USP30 (0.38) | SLC6A2SLC6A4ALDH1A1HDAC3HDAC1 | |
| SCHEMBL1709409 | 0.81 | POLB (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL1709358 | 0.80 | DPEP1 (0.36) | EPHX2SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL1709489 | 0.80 | OPRM1 (0.37) | OPRM1SLC6A2SLC6A4PTGDR2 | |
| SCHEMBL1709407 | 0.79 | TP53 (0.39) | EPHX2OPRM1OPRK1ALDH1A1HDAC1 | |
| SCHEMBL1709480 | 0.79 | NPC1 (0.38) | ALDH1A1 | |
| SCHEMBL1709454 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |