Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032986 | 0.88 | KDM1A (0.34) | OPRM1OPRK1HTR2CHTR2BOPRD1 | |
| SCHEMBL10033138 | 0.83 | SIGMAR1 (0.42) | HTR2CHTR2B | |
| SCHEMBL1709502 | 0.81 | ESR2 (0.35) | — | |
| SCHEMBL1709412 | 0.81 | OPRM1 (0.31) | OPRM1OPRK1HTR2CHTR2BOPRL1 | |
| SCHEMBL1709411 | 0.81 | SIGMAR1 (0.31) | — | |
| SCHEMBL1709413 | 0.79 | MDM2 (0.41) | HTR2CHTR2B | |
| SCHEMBL1709404 | 0.78 | HTR2C (0.34) | HTR2C | |
| SCHEMBL1709403 | 0.78 | HTR2C (0.34) | HTR2C | |
| SCHEMBL1709443 | 0.78 | HTR2C (0.34) | HTR2C | |
| SCHEMBL1709494 | 0.76 | HTR2C (0.35) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |