Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158452 | 0.89 | PDK2 (0.36) | MCL1ACMSDENPP3ENPP1PDK2 | |
| SCHEMBL14912402 | 0.87 | CRHBP (0.39) | PDK2CA1CA2 | |
| SCHEMBL28852694 | 0.86 | MEN1 (0.38) | MCL1ACMSDENPP3ENPP1PDK2 | |
| SCHEMBL19383271 | 0.86 | PDK2 (0.42) | MCL1ACMSDENPP3ENPP1PDK2 | |
| SCHEMBL10034430 | 0.86 | CYP11B1 (0.38) | PDK2CA1CA2 | |
| SCHEMBL16755462 | 0.86 | ALDH1A1 (0.38) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL15463932 | 0.85 | AR (0.33) | MCL1ACMSDENPP3ENPP1PDK2 | |
| SCHEMBL12781884 | 0.85 | PDK2 (0.38) | PDK2CA1CA2 | |
| SCHEMBL23605907 | 0.85 | ALDH1A1 (0.39) | ENPP3ENPP1PDK2 | |
| SCHEMBL17209213 | 0.85 | NTSR1 (0.33) | MCL1ACMSDENPP3ENPP1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11258018-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2022-02-22 | — | — | US | disclosed |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-2875699-B1 | DERIVATES OF 2-DIARYLAMINOFLUOREN AND ORGANIC ELECTRONIC DEVICES COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-9184395-B2 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9184395-B2 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-8980442-B2 | Aromatic amine derivative and organic electroluminescent element using same | MITSUI CHEMICALS, INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-8980442-B2 | Aromatic amine derivative and organic electroluminescent element using same | MITSUI CHEMICALS, INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2415752-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | Mitsui Chemicals, Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120012832-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | MITSUI CHEMICALS, INC. (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120012832-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | MITSUI CHEMICALS, INC. (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | DDT, AFF2, CYP2F1 | MCL1 1771/4885ACMSD 703/4885ENPP3 188/4885 |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | MCL1 1851/4885ACMSD 1011/4885ENPP3 302/4885 |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | ETV6, CYP2C19, AFF2 | MCL1 1851/4885ACMSD 1011/4885ENPP3 302/4885 |
| US-11258018-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | MCL1 1851/4885ACMSD 1011/4885ENPP3 302/4885 |
| US-20120012832-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | MAOA, MAOB, TYR | MCL1 3970/4885ACMSD 1172/4885ENPP3 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.