SCHEMBL10035677

SCHEMBL10035677

CCCc1ccc(C(=O)Nc2cccc3cccc(S(=O)(=O)OC)c23)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CD40 P25942 2/20 0.52
CD40LG P29965 2/20 0.52
ABCG2 Q9UNQ0 4/20 0.48
TRPV1 Q8NER1 5/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
PLK1 P53350 6/20 0.45
ENPP1 P22413 1/20 0.43
PLK3 Q9H4B4 4/20 0.43
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10035673 0.88 ABCG2 (0.57) ABCG2TRPV1SENP8SENP7SENP6
SCHEMBL10035676 0.77 PLK1 (0.57) ABCG2SENP8SENP7SENP6PLK1
SCHEMBL10035663 0.77 SENP8 (0.55) ABCG2TRPV1SENP8SENP7SENP6
SCHEMBL6362788 0.75 LMNA (0.49) CD40CD40LGGAA
SCHEMBL3217784 0.74 HPGD (0.54) NPC1RAB9A
SCHEMBL13599245 0.74 CD40 (0.55) CD40CD40LGABCG2TRPV1PLK1
SCHEMBL12630739 0.71 CA1 (0.46) NPC1GAARAB9A
SCHEMBL13599246 0.71 MMP12 (0.45) ABCG2SENP8SENP7SENP6PLK1
SCHEMBL14539253 0.69 CA1 (0.49) NPC1RAB9A
SCHEMBL14473033 0.69 HDAC1 (0.68) SENP8SENP7SENP6NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110329-B2 Charge controlling agent and toner CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-20070111125-A1 CHARGE CONTROLLING AGENT AND TONER CANON KABUSHIKI KAISHA (JP) 2007-05-17 US disclosed
US-20070111125-A1 CHARGE CONTROLLING AGENT AND TONER CANON KABUSHIKI KAISHA (JP) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070111125-A1 CHARGE CONTROLLING AGENT AND TONER CA2, ACTR2, CA12 CD40 4822/4885CD40LG 4877/4885ABCG2 4241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.