Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12108414 | 0.80 | CA2 (0.52) | NOS3NOS1TSHRCA12CA1 | |
| SCHEMBL14690091 | 0.78 | NOS3 (0.54) | NOS3NOS1PRSS1PRSS2PRSS3 | |
| SCHEMBL41775 | 0.76 | TSHR (0.67) | NOS3NOS1PRSS1PRSS2PRSS3 | |
| SCHEMBL10073625 | 0.76 | TSHR (0.46) | TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL24507952 | 0.75 | CA2 (0.47) | LTA4HCA2ADRA2AADRA2BADRA2C | |
| SCHEMBL18815313 | 0.74 | PRSS1 (0.44) | NOS3NOS1PRSS1PRSS2PRSS3 | |
| SCHEMBL24587489 | 0.74 | NOS3 (0.50) | NOS3NOS1PRSS1PRSS2PRSS3 | |
| SCHEMBL13946507 | 0.74 | NOS3 (0.50) | NOS3NOS1PRSS1PRSS2PRSS3 | |
| SCHEMBL24423474 | 0.74 | NOS3 (0.52) | NOS3NOS1CA12CA1CA2 | |
| SCHEMBL29413339 | 0.73 | TSHR (0.62) | NOS3NOS1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024041586-A1 | PRODRUG OF JAK KINASE INHIBITOR | 启元生物(杭州)有限公司 | 2024-02-29 | — | — | WO | disclosed |
| US-20170320834-A1 | TRIAZABUTADIENES AS CLEAVABLE CROSS-LINKERS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2017-11-09 | — | — | US | disclosed |
| US-9593080-B1 | Triazabutadienes as cleavable cross-linkers | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-03-14 | — | — | US | disclosed |
| US-8362559-B2 | Hybrid molecular electronic devices containing molecule-functionalized surfaces for switching, memory, and sensor applications and methods for fabricating same | WILLIAM MARSH RICE UNIVERSITY (US) | 2013-01-29 | — | — | US | disclosed |
| US-8361908-B2 | Modified surface material, method for preparing same and uses thereof | UNIVERSITE PARIS 7-DENIS DIDEROT (FR) | 2013-01-29 | — | — | US | disclosed |
| US-8207244-B2 | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-06-26 | — | — | US | disclosed |
| US-20120015138-A1 | MODIFIED SURFACE MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF | ALCHIMEDICS (FR) | 2012-01-19 | — | — | US | disclosed |
| US-8053567-B2 | forming undercoatings on semiconductor by polymerizing monomers with diazonium salt which can electrochemical reduction having a polymerization initiator function; in situ free radical polymerization; stents, implants, prostheses; corrosion resistance | Universite Paris 7—Denis Diderot (FR) | 2011-11-08 | — | — | US | disclosed |
| US-20100252824-A1 | Hybrid Molecular Electronic Devices Containing Molecule-Functionalized Surfaces for Switching, Memory, and Sensor Applications and Methods for Fabricating Same | WILLIAM MARSH RICE UNIVERSITY (US) | 2010-10-07 | — | — | US | disclosed |
| US-20080258179-A1 | Hybrid molecular electronic device for switching, memory, and sensor applications, and method of fabricating same | WILLIAM MARSH RICE UNIVERSITY (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080064783-A1 | Modified Surface Material, Method for Preparing Same and Uses Thereof | ALCHIMEDICS (FR) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320834-A1 | TRIAZABUTADIENES AS CLEAVABLE CROSS-LINKERS | WRN, TNKS, JMJD7 | NOS3 4419/4885NOS1 4210/4885PRSS1 3084/4885 |
| US-20080064783-A1 | Modified Surface Material, Method for Preparing Same and Uses Thereof | SOAT2, SOAT1, INMT | NOS3 60/4885NOS1 37/4885PRSS1 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.