Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100598 | 0.87 | HDAC8 (0.46) | NOS3NOS1ALDH1A1HSD17B10TSHR | |
| SCHEMBL26801174 | 0.80 | CA2 (0.52) | NOS3NOS1ALDH1A1HSD17B10TSHR | |
| SCHEMBL14690091 | 0.78 | NOS3 (0.54) | NOS3NOS1ALDH1A1TSHRCA12 | |
| SCHEMBL14690090 | 0.78 | NOS3 (0.54) | NOS3NOS1ALDH1A1TSHRCA12 | |
| SCHEMBL18533548 | 0.78 | TSHR (0.54) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL41775 | 0.76 | TSHR (0.67) | NOS3NOS1TSHRCA12CA1 | |
| SCHEMBL234461 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL27473140 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL24587489 | 0.74 | NOS3 (0.50) | NOS3NOS1TSHRCA12CA1 | |
| SCHEMBL10035756 | 0.74 | NOS3 (0.50) | NOS3NOS1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161506-A | Solid-phase probe for marking terminal alkyne compound and synthesis method and application thereof | 中国科学院兰州化学物理研究所 | 2024-12-20 | — | — | CN | claimed |
| CN-109694472-B | Functional polyether initiator, synthesis thereof and application thereof in polyether synthesis | 万华化学集团股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-119161506-A | Solid-phase probe for marking terminal alkyne compound and synthesis method and application thereof | 中国科学院兰州化学物理研究所 | 2024-12-20 | — | — | CN | disclosed |
| CN-118255763-A | Azo reductase/pH dual response fluorescent compound, and preparation method and application thereof | 南通大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-118005709-A | CDDO-Me/Ozanimod co-prodrug based on azo reductase activation as well as preparation method and application thereof | 南通大学 | 2024-05-10 | — | — | CN | disclosed |
| US-20230270874-A1 | ANTIBODY DRUG CONJUGATE LOADED WITH BINARY TOXINS AND ITS APPLICATION | MABPLEX INTERNATIONAL CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| EP-3950061-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2022-02-09 | — | — | EP | disclosed |
| WO-2021183702-A1 | GPX4 INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING GPX4-MEDIATED DISEASES | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2021-09-16 | — | — | WO | disclosed |
| CN-109694472-B | Functional polyether initiator, synthesis thereof and application thereof in polyether synthesis | 万华化学集团股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-109694472-B | Functional polyether initiator, synthesis thereof and application thereof in polyether synthesis | 万华化学集团股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-2946006-B1 | ENGINEERED BIOCATALYSTS USEFUL FOR CARBAPENEM SYNTHESIS | CODEXIS INC (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017097872-A1 | HYBRID MOLECULE COMPRISING STRUCTURAL AND ACTIVE ELEMENTS OF RESVERATROL AND DIALLYL DISULFIDE | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2017-06-15 | — | — | WO | disclosed |
| EP-2592476-A1 | Antireflective coating forming composition containing vinyl ether compound and polyimide | Nissan Chemical Industries, Ltd. (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-7491732-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080306099-A1 | Prevent transplant rejection; autoimmune diseases | RIGEL PHARMACEUTICALS, INC. | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270874-A1 | ANTIBODY DRUG CONJUGATE LOADED WITH BINARY TOXINS AND ITS APPLICATION | MMAB, TNFSF10, CD47 | NOS3 4703/4885NOS1 4653/4885ALDH1A1 3067/4885 |
| US-20080306099-A1 | Prevent transplant rejection; autoimmune diseases | JAK3, JAK1, JAK2 | NOS3 46/4885NOS1 480/4885ALDH1A1 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.