SCHEMBL10035835

SCHEMBL10035835

O=S(O)c1ccc(-n2nnnc2S)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.38
ALDH1A1 P00352 6/20 0.33
HPGD P15428 4/20 0.33
HTT P42858 3/20 0.33
MAPT P10636 4/20 0.32
POLB P06746 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HSP90AA1 P07900 2/20 0.32
TP53 P04637 1/20 0.32
NLRP1 Q9C000 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
HSD17B10 Q99714 1/20 0.31
PTGS2 P35354 4/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27532832 0.89 ALDH1A1 (0.41) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL12936639 0.81 MAPT (0.38) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL594488 0.77 ALDH1A1 (0.47) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL27515853 0.75 ALDH1A1 (0.46) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL278889 0.75 HPGD (0.52) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL5094713 0.73 HPGD (0.51) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL5148940 0.73 PTGS2 (0.42) LMNAPTGS2
SCHEMBL14655688 0.73 ALDH1A1 (0.53) ALDH1A1HPGDHTTPOLBMEN1
SCHEMBL3294203 0.73 TSHR (0.51) LMNAALDH1A1HPGDHTTMAPT
SCHEMBL8048128 0.73 ALDH1A1 (0.49) LMNAALDH1A1HTTMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8094360-B2 Room temperature molten salt and display element KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-10 US disclosed
US-7864407-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-04 US disclosed
US-20090091234-A1 ROOM TEMPERATURE MOLTEN SALT AND DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-09 US disclosed
US-20080166590-A1 Display Element KONICA MINOLTA HOLDINGS, INC. (JP) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090091234-A1 ROOM TEMPERATURE MOLTEN SALT AND DISPLAY ELEMENT SAV1, TYR, MPST LMNA 4785/4885ALDH1A1 710/4885HPGD 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.