Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593603 | 0.89 | KMT2A (0.54) | CYP1A2KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL14438597 | 0.85 | CYP1A2 (0.49) | CYP1A2KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL16924677 | 0.81 | TDP1 (0.55) | CYP1A2KMT2AMEN1MAPK1HDAC1 | |
| SCHEMBL9334268 | 0.81 | KMT2A (0.80) | CYP1A2KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL30061865 | 0.81 | CYP1A2 (1.00) | CYP1A2CYP2D6CYP2C19SMN1; SMN2HDAC3 | |
| SCHEMBL2318140 | 0.81 | CYP1A2 (1.00) | CYP1A2CYP2D6CYP2C19SMN1; SMN2HDAC3 | |
| SCHEMBL11032522 | 0.79 | CYP1A2 (0.90) | CYP1A2KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL29419458 | 0.79 | CYP1A2 (0.90) | CYP1A2KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL13713632 | 0.78 | AKR1B1 (0.58) | CYP1A2KMT2AMEN1CYP2D6MAPT | |
| SCHEMBL29441770 | 0.78 | KMT2A (1.00) | CYP1A2KMT2AMEN1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110576146-B | Preparation method of coating for sand core for improving casting quality | 含山县荣盛机械铸造有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-110576146-A | preparation method of coating for sand core for improving casting quality | 含山县荣盛机械铸造有限公司 | 2019-12-17 | — | — | CN | claimed |
| CN-110576146-B | Preparation method of coating for sand core for improving casting quality | 含山县荣盛机械铸造有限公司 | 2020-10-23 | — | — | CN | disclosed |
| US-10544324-B2 | Noncovalent bond-modified carbon structure, and carbon structure/polymer composite comprising same | POSCO (KR) | 2020-01-28 | — | — | US | disclosed |
| CN-110576146-A | preparation method of coating for sand core for improving casting quality | 含山县荣盛机械铸造有限公司 | 2019-12-17 | — | — | CN | disclosed |
| US-20160326393-A1 | NONCOVALENT BOND-MODIFIED CARBON STRUCTURE, AND CARBON STRUCTURE/POLYMER COMPOSITE COMPRISING SAME | POSCO (KR) | 2016-11-10 | — | — | US | disclosed |
| US-20160326393-A1 | NONCOVALENT BOND-MODIFIED CARBON STRUCTURE, AND CARBON STRUCTURE/POLYMER COMPOSITE COMPRISING SAME | POSCO (KR) | 2016-11-10 | — | — | US | disclosed |
| EP-3088356-A1 | NONCOVALENT BOND-MODIFIED CARBON STRUCTURE, AND CARBON STRUCTURE/POLYMER COMPOSITE COMPRISING SAME | Posco (KR) | 2016-11-02 | — | — | EP | disclosed |
| US-20150099800-A1 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | NIH - DEITR | 2015-04-09 | — | — | US | disclosed |
| WO-2013177492-A2 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | NORTHEASTERN UNIVERSITY (US) | 2013-11-28 | — | — | WO | disclosed |
| US-7868135-B2 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | BIOWEST THERAPEUTICS INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| EP-2147925-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2010-01-27 | — | — | EP | disclosed |
| CN-1839150-A | Lipopeptide antibacterial derivative composition and application method thereof | MIGENIX INC (CA) | 2006-09-27 | — | — | CN | disclosed |
| EP-1656390-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2006-05-17 | — | — | EP | disclosed |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2005-07-14 | — | — | US | disclosed |
| WO-2005000878-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | NRDC, NOD2, NGLY1 | CYP1A2 4441/4885KMT2A 4429/4885MEN1 3085/4885 |
| US-20150099800-A1 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | PNLIP, LIPE, LIPC | CYP1A2 2750/4885KMT2A 3785/4885MEN1 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.