Dithiazanine

Dithiazanine

SCHEMBL10035960

CCN1/C(=C/C=C/C=C/c2sc3ccccc3[n+]2CC)Sc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 1.00
▸ MEN1 O00255 6/20 1.00
▸ HTT P42858 5/20 1.00
▸ BLM P54132 4/20 1.00
▸ NPC1 O15118 6/20 0.98
▸ RAB9A P51151 6/20 0.98
▸ MAPT P10636 4/20 0.98
▸ THRB P10828 3/20 0.98
▸ PKM P14618 3/20 0.98
▸ NPSR1 Q6W5P4 3/20 0.98
▸ ALDH1A1 P00352 3/20 0.98
▸ POLB P06746 2/20 0.98
▸ RECQL P46063 2/20 0.98
▸ SMN1; SMN2 Q16637 2/20 0.98
▸ TDP1 Q9NUW8 2/20 0.98
▸ USP2 O75604 2/20 0.98
▸ ALOX12 P18054 2/20 0.98
▸ CTNNB1 P35222 2/20 0.98
▸ KDM4E B2RXH2 1/20 0.98
▸ LMNA P02545 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dithiazanine SCHEMBL17278433 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
Dithiazanine SCHEMBL1567134 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
SCHEMBL10110715 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
SCHEMBL13898198 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
SCHEMBL30356388 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
SCHEMBL1598509 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
SCHEMBL12868063 1.00 KMT2A (1.00) KMT2AMEN1HTTBLMNPC1
Iodide SCHEMBL335663 0.99 MEN1 (1.00) KMT2AMEN1HTTBLMNPC1
Dithiazanine SCHEMBL22877 0.99 MEN1 (1.00) KMT2AMEN1HTTBLMNPC1
Bromide SCHEMBL11693039 0.99 KMT2A (0.98) KMT2AMEN1HTTBLMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372310-A1 Flavi-Block: A Pan-Flavivirus Inhibitor BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) 2023-11-23 — — US disclosed
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA UNIV JEFFERSON (US) 2023-05-18 — — US disclosed
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA UNIV JEFFERSON (US) 2023-05-18 — — US disclosed
US-9465290-B2 Near-infrared absorbing film compositions GLOBALFOUNDRIES INC. (KY) 2016-10-11 — — US disclosed
US-20160263249-A1 NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2016-09-15 — — US disclosed
US-20140210034-A1 NEAR-INFRARED ABSORBING FILM COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-31 — — US disclosed
US-8772376-B2 Near-infrared absorbing film compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-08 — — US disclosed
EP-1781675-B1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES INC (US) 2014-03-26 — — EP disclosed
WO-2013090529-A1 NEAR-INFRARED ABSORBING FILM COMPOSITION FOR LITHOGRAPHIC APPLICATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-06-20 — — WO disclosed
US-20130157463-A1 NEAR-INFRARED ABSORBING FILM COMPOSITION FOR LITHOGRAPHIC APPLICATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-20 — — US disclosed
US-8008522-B2 Phosphonate fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2011-08-30 — — US disclosed
US-20110159605-A1 Surface Grafted Conjugated Polymers UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-06-30 — — US disclosed
US-20110042771-A1 Near-Infrared Absorbing Film Compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-02-24 — — US disclosed
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2010-10-14 — — US disclosed
US-7767834-B2 Phosphonylated fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2010-08-03 — — US disclosed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 — — US disclosed
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2008-08-28 — — US disclosed
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 — — US disclosed
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 — — US disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 KMT2A 3091/4885MEN1 1647/4885HTT 1730/4885
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 KMT2A 3036/4885MEN1 1539/4885HTT 1743/4885
US-20230150960-A1 COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA TFAM, COX5A, UQCRC1 KMT2A 3675/4885MEN1 2633/4885HTT 2179/4885
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 KMT2A 3091/4885MEN1 1647/4885HTT 1730/4885
US-20230372310-A1 Flavi-Block: A Pan-Flavivirus Inhibitor MAVS, EIF2AK2, BLVRB KMT2A 1614/4885MEN1 4451/4885HTT 2552/4885
US-20160263249-A1 NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF CD68, MSR1, CD47 KMT2A 4412/4885MEN1 498/4885HTT 3209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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