⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002486 | 0.81 | LTA4H (0.32) | — | |
| SCHEMBL10024564 | 0.69 | — | — | |
| SCHEMBL10024565 | 0.68 | — | — | |
| SCHEMBL1004580 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL8944317 | 0.61 | APP (0.38) | — | |
| SCHEMBL14492553 | 0.60 | — | — | |
| SCHEMBL16350148 | 0.60 | CA12 (0.32) | — | |
| SCHEMBL8944216 | 0.59 | APP (0.37) | — | |
| SCHEMBL10984457 | 0.58 | DUT (0.38) | — | |
| SCHEMBL1002484 | 0.58 | BBOX1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237670-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2237673-B1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-8470894-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS (US) | 2013-06-25 | — | — | US | disclosed |
| US-8263669-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120142535-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2012-06-07 | — | — | US | disclosed |
| US-20110028569-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-02-03 | — | — | US | disclosed |
| US-20110021644-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-01-27 | — | — | US | disclosed |
| EP-2237673-A2 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | Momentive Performance Materials Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| US-20090173912-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| US-20090176893-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| WO-2009085297-A2 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | WO | disclosed |