SCHEMBL10039251

SCHEMBL10039251

CC(C)OP(=S)(OC(C)C)SCC(C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
GABRR1 P24046 2/20 0.32
CYP1A2 P05177 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20315183 0.83 ALDH1A1 (0.46) ALDH1A1KDM4ETSHRGABRR1CYP1A2
SCHEMBL1605068 0.81 ALDH1A1 (0.35) ALDH1A1KDM4ETSHR
SCHEMBL15722832 0.79 GABRR1 (0.33) KDM4EGABRR1CYP1A2
SCHEMBL2037811 0.79 ALDH1A1 (0.39) ALDH1A1KDM4ETSHRGABRR1CYP1A2
SCHEMBL11216532 0.77 ALDH1A1 (0.40) ALDH1A1KDM4ETSHRMAPT
SCHEMBL17677610 0.76
SCHEMBL29159302 0.76 ALDH1A1 (0.32) ALDH1A1KDM4ETSHR
SCHEMBL19253878 0.76 GRIK1 (0.38) ALDH1A1
SCHEMBL1161348 0.74 TSHR (0.38) ALDH1A1KDM4ETSHRCYP1A2MAPT
SCHEMBL18193251 0.74 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118725938-B Antiwear system for improved copper corrosion 雅富顿化学公司 2025-01-28 CN disclosed
EP-4438701-A1 ANTIWEAR SYSTEM FOR IMPROVED COPPER CORROSION Afton Chemical Corporation (US) 2024-10-02 EP disclosed
EP-4438611-A1 THIOPHOSPHORIC ACID PRODUCTS FOR ANTIWEAR ADDITIVES Afton Chemical Corporation (US) 2024-10-02 EP disclosed
CN-118725938-A Antiwear system for improved copper corrosion 雅富顿化学公司 2024-10-01 CN disclosed
US-11958875-B1 Thiophosphoric acid products for antiwear additives AFTON CHEMICAL CORPORATION (US) 2024-04-16 US disclosed
US-11884893-B1 Antiwear system for improved copper corrosion AFTON CHEMICAL CORPORATION (US) 2024-01-30 US disclosed
US-20180171257-A1 ALKOXYLATED AMIDES, ESTERS, AND ANTI-WEAR AGENTS IN LUBRICANT COMPOSITIONS AND RACING OIL COMPOSITIONS BASF SE (DE) 2018-06-21 US disclosed
US-9920275-B2 Alkoxylated amides, esters, and anti-wear agents in lubricant compositions and racing oil compositions BASF SE (DE) 2018-03-20 US disclosed
US-9909081-B2 Alkoxylated amides, esters, and anti-wear agents in lubricant compositions BASF SE (DE) 2018-03-06 US disclosed
US-9677023-B2 Lubricating oil compositions containing seal compatibility additives and sterically hindered amines BASF SE (DE) 2017-06-13 US disclosed
WO-2014078702-A1 LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY BASF SE (DE) 2014-05-22 WO disclosed
US-20140142010-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
US-20140142009-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
US-20140142008-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
US-20140142011-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
WO-2014078691-A1 LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS BASF SE (DE) 2014-05-22 WO disclosed
US-20140142010-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
WO-2013009381-A1 LUBRICANT COMPOSITION HAVING IMPROVED ANTIWEAR PROPERTIES BASF SE (DE) 2013-01-17 WO disclosed
US-20120035088-A1 LUBRICANT COMPOSITION HAVING IMPROVED ANTIWEAR PROPERTIES BASF SE (DE) 2012-02-09 US disclosed
US-20120035088-A1 LUBRICANT COMPOSITION HAVING IMPROVED ANTIWEAR PROPERTIES BASF SE (DE) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884893-B1 Antiwear system for improved copper corrosion USP13, AP2S1, IWS1 ALDH1A1 1378/4885KDM4E 4128/4885TSHR 3155/4885
US-11958875-B1 Thiophosphoric acid products for antiwear additives TST, ATIC, DNAJC13 ALDH1A1 1620/4885KDM4E 3939/4885TSHR 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.