Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19709261 | 0.86 | PDE2A (0.58) | PDE2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5827084 | 0.86 | PDE2A (0.58) | PDE2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL2703655 | 0.86 | PDE2A (0.58) | PDE2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL10039657 | 0.85 | KMT2A (0.57) | MEN1KMT2ANPC1RAB9APDE2A | |
| SCHEMBL17149927 | 0.83 | KMT2A (0.61) | MEN1KMT2APDGFRBPDGFRAFLT3 | |
| SCHEMBL10039633 | 0.82 | KMT2A (0.72) | MEN1KMT2AFLT3NPC1RAB9A | |
| SCHEMBL17149669 | 0.80 | KMT2A (0.64) | MEN1KMT2APDGFRBPDGFRAFLT3 | |
| SCHEMBL10039780 | 0.79 | PDE2A (0.55) | PDGFRBPDGFRAPDE2ALMNAGAA | |
| SCHEMBL11827562 | 0.79 | KMT2A (0.62) | MEN1KMT2ANPC1RAB9AROCK2 | |
| SCHEMBL10039649 | 0.78 | PYGL (0.53) | MEN1KMT2AFLT3PDE2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |