Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039633 | 0.89 | KMT2A (0.72) | KMT2AMEN1RCE1ROCK2ROCK1 | |
| SCHEMBL10039604 | 0.85 | MEN1 (0.56) | KMT2AMEN1RCE1ROCK2ROCK1 | |
| SCHEMBL2703655 | 0.80 | PDE2A (0.58) | KDM4EMAPK1PDE2ALMNAGAA | |
| SCHEMBL19709261 | 0.80 | PDE2A (0.58) | KDM4EMAPK1PDE2ALMNAGAA | |
| SCHEMBL5827084 | 0.80 | PDE2A (0.58) | KDM4EMAPK1PDE2ALMNAGAA | |
| SCHEMBL10039792 | 0.78 | KMT2A (0.61) | KMT2AMEN1RCE1ROCK2ROCK1 | |
| SCHEMBL10039780 | 0.75 | PDE2A (0.55) | POLBPDE2ALMNAGAA | |
| SCHEMBL11827562 | 0.75 | KMT2A (0.62) | KMT2AMEN1ROCK2ROCK1NPC1 | |
| SCHEMBL10039649 | 0.74 | PYGL (0.53) | KMT2AMEN1PDE2ALMNAGAA | |
| SCHEMBL26098783 | 0.73 | PDE2A (0.57) | PDE2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |