Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | CCKAR | P32238 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2703655 | 0.85 | PDE2A (0.58) | DRD2TAS1R3TAS1R1GAAKDM4E | |
| SCHEMBL5827084 | 0.85 | PDE2A (0.58) | DRD2TAS1R3TAS1R1GAAKDM4E | |
| SCHEMBL19709261 | 0.85 | PDE2A (0.58) | DRD2TAS1R3TAS1R1GAAKDM4E | |
| SCHEMBL10039653 | 0.84 | DRD2 (0.58) | DRD2TAS1R3TAS1R1PYGLGAA | |
| SCHEMBL10039649 | 0.80 | PYGL (0.53) | PYGLGAALMNA | |
| SCHEMBL17149629 | 0.77 | MEN1 (0.64) | DRD2TAS1R3TAS1R1PYGLGAA | |
| SCHEMBL6883379 | 0.77 | MEN1 (0.64) | DRD2TAS1R3TAS1R1PYGLGAA | |
| SCHEMBL19476075 | 0.77 | MEN1 (0.64) | DRD2TAS1R3TAS1R1PYGLGAA | |
| SCHEMBL29949076 | 0.77 | DRD2 (0.68) | DRD2TAS1R3TAS1R1PYGLGAA | |
| SCHEMBL13753384 | 0.77 | DRD2 (0.68) | DRD2TAS1R3TAS1R1PYGLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |