SCHEMBL10040377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27209638	0.88	ALDH1A1 (0.41)	ALDH1A1GPX4KDM4ENPC1POLB
	SCHEMBL2777513	0.87	ALDH1A1 (0.32)	ALDH1A1KDM4ENPC1POLBMAPT
	SCHEMBL2778008	0.83	ALDH1A1 (0.35)	ALDH1A1
	SCHEMBL75085	0.82	CHRM2 (0.38)	ALDH1A1GPX4ATM
	SCHEMBL18714190	0.82	CHRM2 (0.38)	ALDH1A1GPX4ATM
	SCHEMBL18643942	0.82	CHRM2 (0.38)	ALDH1A1GPX4ATM
	SCHEMBL18623591	0.81	ALDH1A1 (0.40)	ALDH1A1ATM
	SCHEMBL11964233	0.80	ALDH1A1 (0.38)	ALDH1A1GPX4KDM4ENPC1POLB
	SCHEMBL13431243	0.80	GPX4 (0.31)	GPX4
	SCHEMBL75446	0.79	ALDH1A1 (0.34)	ALDH1A1KDM4ENPC1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.