Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040555 | 0.91 | LMNA (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10040667 | 0.86 | EPHX2 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10040551 | 0.85 | SMO (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10040550 | 0.83 | SMO (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10040547 | 0.83 | SMO (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10040536 | 0.83 | SPR (0.45) | LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL10040620 | 0.82 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL1653033 | 0.82 | SPR (0.45) | LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL10040543 | 0.82 | MAPT (0.52) | HSD11B1SMN1; SMN2GAA | |
| SCHEMBL12784107 | 0.81 | SMO (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308869-B1 | AZOLE COMPOUND | ASTELLAS PHARMA INC (JP) | 2012-09-19 | — | — | EP | disclosed |
| US-8207199-B2 | Azole compound | ASTELLAS PHARMA INC. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-8207199-B2 | Azole compound | ASTELLAS PHARMA INC. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20110118311-A1 | AZOLE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110118311-A1 | AZOLE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118311-A1 | AZOLE COMPOUND | FAAH, FAAH2, TRPV1 | TUBB4A 1506/4885TUBB 1819/4885TUBA3C 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.