Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1541679 | 0.83 | KMT2A (0.46) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL1541524 | 0.79 | ALDH1A1 (0.52) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL4568619 | 0.76 | KMT2A (0.37) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL28728423 | 0.76 | TSHR (0.67) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL2082945 | 0.75 | PDE4D (0.51) | ALDH1A1MAPTNPSR1KMT2AMEN1 | |
| SCHEMBL6692873 | 0.72 | ALDH1A1 (0.56) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL9124019 | 0.71 | ALDH1A1 (0.67) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL3874391 | 0.70 | ALDH1A1 (0.60) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL6697515 | 0.70 | ALDH1A1 (0.54) | FFAR1ALDH1A1MAPTHTTHSP90AA1 | |
| SCHEMBL9092851 | 0.69 | GRM5 (0.56) | FFAR1ALDH1A1MAPTHTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101760-B2 | Glucocorticoid receptor modulator and methods of use | ELI LILLY AND COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100069425-A1 | GLUCOCORTICOID RECEPTOR MODULATOR AND METHODS OF USE | ELI LILLY AND COMPANY (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069425-A1 | GLUCOCORTICOID RECEPTOR MODULATOR AND METHODS OF USE | NR3C1, NR3C2, MC2R | FFAR1 138/4885ALDH1A1 2595/4885MAPT 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.