Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 18/20 | 0.72 |
| ▸ | ADRA2B | P18089 | 18/20 | 0.72 |
| ▸ | ADRA2C | P18825 | 18/20 | 0.72 |
| ▸ | MAOA | P21397 | 6/20 | 0.65 |
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13431743 | 0.80 | MAOA (0.67) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL17887853 | 0.76 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL14645137 | 0.73 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL29598740 | 0.73 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| Biphenyline SCHEMBL29519295 | 0.72 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL4543645 | 0.70 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL10013416 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL2961408 | 0.69 | ALDH1A1 (0.65) | — | |
| SCHEMBL3335019 | 0.69 | ALDH1A1 (0.69) | — | |
| SCHEMBL3360145 | 0.67 | NISCH (0.50) | ADRA2AADRA2BADRA2CMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101779-B2 | Enantioselective synthesis of (+) and (–)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100087657-A1 | ENANTIOSELECTIVE SYNTHESIS OF (+) AND (-)-2-[1-(2,6-DICHLOROPHENOXY)-ETHYL]-1,3-DIAZACYCLOPENT-2-3ENE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087657-A1 | ENANTIOSELECTIVE SYNTHESIS OF (+) AND (-)-2-[1-(2,6-DICHLOROPHENOXY)-ETHYL]-1,3-DIAZACYCLOPENT-2-3ENE | CYP2E1, CYP2D6, CYP2C9 | ADRA2A 197/4885ADRA2B 286/4885ADRA2C 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.